Candida Auris: A New Fungal Superbug Emerging As A Global Threat

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The new bug on the block is Candida auris. This is different from the common Candida albicans, which frequently causes vaginal yeast infections in women, diaper rash or "thrush," an oral infection often complicating antibiotic treatment. C. albicans is susceptible to many anti-fungals; C. auris is not, and often is resistant to multiple classes of antibiotics. The other disturbing trait is C. auris ability […]

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  • op 28 september 2017
  • door dTHIP redactie

Next-Generation Sequence Analysis Reveals Transfer of Methicillin Resistance to a Methicillin-Susceptible Staphylococcus aureus Strain That Subsequently Caused a Methicillin-Resistant Staphylococcus aureus Outbreak: a Descriptive Study.

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Resistance to methicillin in Staphylococcus aureus is caused primarily by the mecA gene, which is carried on a mobile genetic element, the staphylococcal cassette chromosome mec (SCCmec). Horizontal transfer of this element is supposed to be an important factor in the emergence of new clones of methicillin-resistant Staphylococcus aureus (MRSA) but has been rarely observed in real time. In 2012, an outbreak occurred involving a […]

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  • op 13 september 2017
  • door dTHIP redactie

High prevalence of the mcr-1 gene in retail chicken meat in the Netherlands in 2015

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Recently, plasmid-mediated colistin resistance was reported in humans, animals and food. We studied the presence of mcr-1 and mcr-2 in Dutch retail chicken meat. The prevalence of mcr-1 was 24,8% (53/214), whereas mcr-2 was not found. The presence of mcr-1-positive Enterobacteriaceae was confirmed by culture in 34/53 samples (64,2%). The prevalence depended on the supermarket chain and was lower in free-range chicken samples. The […]

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  • door dTHIP redactie

Trends in antimicrobial resistance in bloodstream infection isolates at a large urban hospital in Malawi (1998–2016): a surveillance study

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Background: Bacterial bloodstream infection is a common cause of morbidity and mortality in sub-Saharan Africa, yet few facilities are able to maintain long-term surveillance. The Malawi-Liverpool-Wellcome Trust Clinical Research Programme has done sentinel surveillance of bacteraemia since 1998. We report long-term trends in bloodstream infection and antimicrobial resistance from this surveillance. Methods: In this surveillance study, […]

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  • door dTHIP redactie

A fatal outbreak of ST11 carbapenem-resistant hypervirulent Klebsiella pneumoniae in a Chinese hospital: a molecular epidemiological study

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Background: Hypervirulent Klebsiella pneumoniae strains often cause life-threatening community-acquired infections in young and healthy hosts, but are usually sensitive to antibiotics. In this study, we investigated a fatal outbreak of ventilator-associated pneumonia caused by a new emerging hypervirulent K pneumoniae strain.   Methods: The outbreak occurred in the integrated intensive care unit of a new branch of the Second Affiliated Hospital […]

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  • door dTHIP redactie

The incidence of decolonizing patients of Staphylococcus aureus nasal carriage undergoing an orthopaedic surgery in the Netherlands.

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Introduction: Surgical site infections (SSIs) are a serious complication in orthopaedic surgery which may lead to permanent disability and even mortality. Nasal carriage of Staphylococcus aureus (S.aureus) is associated with an increased risk for development of SSI in orthopaedic surgery. The risk for SSI can be reduced by perioperative decolonization of S. aureus carriage. This study […]

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  • door Corianne Meijer

Abstracts from the 4th International Conference on Prevention & Infection Control (ICPIC 2017)

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Klik hier voor de ICPIC 2017 abstracts. Bron: Antimicrobial Resistance & Infection Control 2017 6(Suppl 3):52

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  • op 11 juli 2017
  • door dTHIP redactie

HBO Kennisbank

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De HBO Kennisbank biedt toegang tot de resultaten van onderzoek van hogescholen en maakt deze beschikbaar voor hergebruik. Hiermee vergemakkelijkt de HBO Kennisbank de uitwisseling tussen onderzoek, onderwijs, bedrijfs- en beroepsleven en maatschappij. De deelnemende hogescholen, SURF en het Samenwerkingsverband Hogeschool Bibliotheken werken samen om de resultaten, van met publieke middelen gefinancierd onderzoek, vrij beschikbaar te stellen op de HBO […]

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  • door dTHIP redactie

Healthcare personnel intestinal colonization with multidrug-resistant organisms

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OBJECTIVES: This study aims to assess the association between patient contact and intestinal carriage of multidrug-resistant organisms (MDRO) by sampling healthcare personnel (HCP) and staff without patient contact. METHODS: For this observational study, we recruited 400 HCP who worked in our 200-bed research hospital and 400 individuals without patient contact between November 2013 and February […]

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  • door dTHIP redactie

Microbiological problems and biofilms associated with Mycobacterium chimaera in heater e cooler units used for cardiopulmonary bypass

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The role of heater–cooler units (HCUs) in the transmission of Mycobacterium chimaera during open heart surgery has been recognized since 2013. Subsequent investigations uncovered a remarkable global outbreak reflecting the wide distribution of implicated devices. HCUs are an essential component of cardiopulmonary bypass operations and their withdrawal would severely affect capacity for life-saving cardiac surgery. […]

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  • door Corianne Meijer