Beyond the hospital infection control guidelines: a qualitative study using positive deviance to characterize gray areas and to achieve efficacy and clarity in the prevention of healthcare-associated infections

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Background: The literature is replete with attempts to design and promote customized guidelines to reduce infections during the care continuum. Paradoxically, these efforts sometimes result in gray areas where many staff members are unaware of what is required of them, which then leads to confusion, frustration, and uncertainty. We coined the phrase “gray areas” in this context to […]

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  • op 29 oktober 2018
  • door dTHIP redactie

A large, refractory nosocomial outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli demonstrates carbapenemase gene outbreaks involving sink sites require novel approaches to infection control

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Carbapenem-resistant Enterobacteriaceae (CRE) are a health threat, but effective control interventions remain unclear. Hospital wastewater sites are increasingly highlighted as important potential reservoirs. We investigated a large Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli (KPC-EC) outbreak and wider CRE incidence trends over eight years in the Central Manchester Foundation NHS Trust (CMFT), UK, to determine the impact of Infection Prevention and Control […]

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Increased Detection Of Carbapenemase-Producing Enterobacteriaceae On Post-Clean Sampling Of Burns Units Wet Surfaces

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Wet surface biofilms are a potential reservoir for multidrug-resistant Gram-negative organisms, including carbapenamase-producing Enterobacteriaceae (CPE). Recognition of environmental sources is important in reducing secondary patient transmission. We report the increased detection of bla-IMP-4+ CPE in environmental samples from floor drains in Burns Unit shower rooms, when collected following cleaning as compared to pre-cleaning. We propose that disruption of […]

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  • op 28 oktober 2018
  • door dTHIP redactie

Preoperative oral antibiotic prophylaxis reduces surgical site infections after elective colorectal surgery: results from a before-after study

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Background: Surgical site infections (SSI) are common complications after colorectal procedures and remain an important source of morbidity and costs. Preoperative oral antibiotic prophylaxis is a potential infection control strategy, but its effectiveness without simultaneous use of mechanical bowel preparation (MBP) is unclear. In this study, we aimed to determine whether preoperative oral antibiotics reduce the […]

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NTMM uitgave met thema “Antimicrobieel stewardship”

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De derde uitgave van het Nederland Tijdschrift voor Medische Microbiologie (NTMM) heeft een hele uitgave met als thema ‘Antimicrobieel stewardship in de Nederlandse praktijk’. Klik hier en ga direct naar de website. Alle tijdschriften zijn toegankelijk zonder in te loggen.    

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  • op 3 oktober 2018
  • door dTHIP redactie

Welke handalcohol is beter… best

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Zoals we allen weten zijn er thans veel handalcoholen op de markt. Allerlei leveranciers presenteren hun handalcohol als de beste. Bactericide, virucide, met toelatingsnummer, toegestaan als desinfectans in ziekenhuizen en zorginstellingen, toegestaan voor preoperatieve handdesinfectie. Kortom, de grote diversiteit aan handalcoholen maakt een gerichte keuze erg moeilijk. De vergelijking van de vele bomen die het […]

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  • op 26 september 2018
  • door dTHIP redactie

Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) isolated from bean sprouts in the Netherlands

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Community-acquired carriage and infections due to extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) are increasing worldwide, resulting in increased morbidity, mortality and healthcare costs. The origins of community-acquired ESBL-E car- riage and infections remain unclear. Bean sprouts are a potential source of Enterobacteria- ceae for the community, as illustrated by outbreaks of pathogenic Enterobacteriaceae in the past. The current study focuses on contamination […]

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  • op 9 september 2018
  • door dTHIP redactie

Prevalence of healthcare-associated infections in Dutch nursing homes: follow up 2010 – 2017

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Following the first point prevalence study in Dutch nursing homes conducted each November from 2007 to 2009, we conducted a follow-up point prevalence study of healthcare-associated infections (HAIs) each November from 2010 to 2017. Similar methods and criteria were used. Resident characteristics were recorded, data collection was performed by the attending elderly care physicians, via […]

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  • op 7 september 2018
  • door dTHIP redactie

Resurgence risk for measles, mumps and rubella in France in 2018 and 2020

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Large measles and mumps outbreaks recently occurred throughout Europe and the United States. Aim: Our aim was to estimate and map the risk of resurgence for measles, mumps and rubella in France. Methods: We used a multi-cohort model combining seroprevalence information, vaccine cover- age and social contact data. Results: The overall out- break risk for France in 2018 was highest for […]

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  • op 29 augustus 2018
  • door dTHIP redactie

Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis

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Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient populations in hospitals around the world. Intensive care unit (ICU) patients are particularly susceptible to nosocomial infections due to indwelling devices such as intravascular catheters, drains, and intratracheal tubes for mechani- cal ventilation. The increased vulnerability of infected ICU patients demonstrates the importance of […]

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