Worldwide practices on flexible endoscope reprocessing

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Background Endoscopy related infections represent an important threat for healthcare systems worldwide. Recent outbreaks of infections with multidrug resistant micro-organisms have highlighted the problems of contaminated endoscopes. Endoscopes at highest risk for contamination have intricate mechanisms, multiple internal channels and narrow lumens that are especially problematic to clean. In light of raised awareness about the […]

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  • op 4 januari 2019
  • door Corianne Meijer

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza

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Abstract These clinical practice guidelines are an update of the guidelines published by the Infectious Diseases Society of America (IDSA) in 2009, prior to the 2009 H1N1 influenza pandemic. This document addresses new information regarding diagnostic testing, treatment and chemoprophylaxis with antiviral medications, and issues related to institutional outbreak management for seasonal influenza. It is […]

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  • door Corianne Meijer

Simplifying the WHO protocol: Three steps versus six steps for performance of hand hygiene – a cluster-randomized trial.

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BACKGROUND: In an experimental setting, a simplified 3-step hand hygiene technique for applying alcohol-based hand rub was non-inferior in terms of reduction of bacterial counts as compared to the conventional WHO-6-step technique. We therefore compared compliance and microbiological efficacy between both hand hygiene techniques in routine clinical practice. METHODS: We performed a cluster-randomized trial from […]

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  • op 17 december 2018
  • door dTHIP redactie

The preventable proportion of healthcare-associated infections 2005–2016: Systematic review and meta-analysis

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Objective: The preventable proportion of healthcare-associated infections (HAIs) may decrease over time as standards of care improve. We aimed to assess the proportion of HAIs prevented by multifaceted infection control interventions in different economic settings. Methods: In this systematic review and meta-analysis, we searched OVID Medline, EMBASE, CINAHL, PubMed, and The Cochrane Library for studies […]

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  • door dTHIP redactie

Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017

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Antimicrobials are commonly used in acute care hospitals for the treatment of both community-acquired and healthcare-associated infections (HAIs), and for surgical prophylaxis [1]. Studies have indicated that some antimicrobial use may be unnecessary and in instances when use is required, the selection, dose, route of administration and duration of treatment may be inappropriate [2,3]. Through […]

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  • door dTHIP redactie

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis

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Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed to estimate the burden of infections caused by antibiotic-resistant bacteria of public health concern in countries of the EU and European Economic Area (EEA) in 2015, measured in number of cases, attributable deaths, and disability-adjusted […]

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  • door dTHIP redactie

Hier dragen we goede hygiëne op handen

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Werk je in de zorgsector? Dan is goede handhygiëne van essentieel belang. Handen vormen namelijk de belangrijkste overdrachtsweg van micro-organismen. Handhygiëne is de meest doeltreffende maatregel ter preventie van zorginfecties en de verspreiding van (multiresistente) micro-organismen (onder andere bacteriën, virussen en schimmels). Met goede handhygiëne voorkom je enerzijds besmetting van de bewoner en van jezelf, […]

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  • door dTHIP redactie

The quality of studies evaluating antimicrobial stewardship interventions: a systematic review

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Antimicrobial stewardship aims to optimise antibiotic use and minimise selection of antimicrobial resistance. The methodological quality of published studies in this field is unknown. Our objective was to perform a comprehensive systematic review of antimicrobial stewardship research design and identify features which limit validity and translation of research findings into clinical practice. We extracted data on […]

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  • op 26 november 2018
  • door dTHIP redactie

Hand Hygiene in hospitals: Anatomy of a revolution.

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Healthcare-associated infections (HAI) affect hundreds of millions of individuals worldwide. Performing hand hygiene is widely accepted as a key strategy of infection prevention and control (IPC) to prevent HAI, as healthcare workers' contaminated hands are the vehicle most often implicated in the cross-transmission of pathogens in healthcare. In the last 20 years, a paradigm shift has occurred in handhygiene: […]

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  • door dTHIP redactie

Hand hygiene in intensive care units: a matter of time?

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Healthcare-associated infections are a frequent threat to patient safety and cause significant disease burden. The most important single preventive measure is hand hygiene (HH). Barriers to adherence with HH recommendations include structural aspects, knowledge gaps, and organizational issues, especially a lack of time in daily routine.

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  • op 25 november 2018
  • door dTHIP redactie