The incidence of decolonizing patients of Staphylococcus aureus nasal carriage undergoing an orthopaedic surgery in the Netherlands.

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Introduction: Surgical site infections (SSIs) are a serious complication in orthopaedic surgery which may lead to permanent disability and even mortality. Nasal carriage of Staphylococcus aureus (S.aureus) is associated with an increased risk for development of SSI in orthopaedic surgery. The risk for SSI can be reduced by perioperative decolonization of S. aureus carriage. This study […]

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  • op 13 september 2017
  • door Corianne Meijer

Healthcare personnel intestinal colonization with multidrug-resistant organisms

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OBJECTIVES: This study aims to assess the association between patient contact and intestinal carriage of multidrug-resistant organisms (MDRO) by sampling healthcare personnel (HCP) and staff without patient contact. METHODS: For this observational study, we recruited 400 HCP who worked in our 200-bed research hospital and 400 individuals without patient contact between November 2013 and February […]

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  • op 11 juli 2017
  • door dTHIP redactie

Multidrug-resistant organisms detected in refugee patients admitted to a university hospital

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Multidrug-resistant Gram-negative bacteria (MDR GNB) were found to colonise 60.8% (95% confidence interval: 52.3–68.9) of 143 refugee patients mainly from Syria (47), Afghanistan (29), and Somalia (14) admitted to the University Hospital Frankfurt, Germany, between June and December 2015. This percentage exceeds the prevalence of MDR GNB in resident patients four–fold. Healthcare personnel should be […]

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  • op 23 maart 2016
  • door dTHIP redactie

Adjustment of the MRSA Search and Destroy policy for outpatients in the Netherlands: a prospective cohort study with repeated prevalence measurements

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In the Netherlands a successful MRSA Search and Destroy policy is applied in healthcare institutes. We determined the effect of an adjustment in the MRSA Search and Destroy policy for patients in the outpatient clinic on the MRSA transmission to health care workers (HCW). In June 2008 an adjustment in the policy for outpatients was introduced in […]

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  • op 30 juli 2014
  • door dTHIP redactie

Acquisition of carbapenemase-producing Enterobacteriaceae by healthy travellers to India, France, February 2012 to March 2013

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Healthy travellers to countries where carbapenemases-producing Enterobacteriaceae (CPE) are endemic might be at risk for their acquisition, even without contact with the local healthcare system. Here, we report the acquisition of CPE (two OXA-181, one New Delhi metallo-beta-lactamase 1 (NDM-1)) in three healthy travellers returning from India. The duration of CPE intestinal carriage was less […]

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  • op 2 juli 2014
  • door dTHIP redactie

Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes

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Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic resistance among pathogens. This review aims to give an overview of the major horizontal transfer mechanisms and their evolution and then demonstrate the human lower gastro-intestinal tract as an environment in which horizontal gene transfer of resistance determinatns occurs. Finally, implications for antibiotic […]

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  • door dTHIP redactie

Europese studie: MRSA is vooral een ziekenhuisbacterie

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In huisartsenpraktijken van negen Europese landen komt MRSA maar weinig voor. In Europa is meticilline-resistente Staphylococcus aureus (MRSA) dus vooral een ziekenhuisbacterie, zo blijkt uit een publicatie van onderzoekers van de Universiteiten van Maastricht, Nottingham en Antwerpen, en het NIVEL in The Lancet Infectious Diseases. De bacterie Staphylococcus aureus zit bij ongeveer een kwart van […]

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  • op 24 april 2013
  • door dTHIP redactie

Baasje deelt veel bacteriën met hond

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Hondenbaasjes delen meer huidbacteriën met hun hond dan met hun eigen kinderen. Dat blijkt uit een studie naar bacteriepopulaties in en op de lichamen van gezinsleden en hun trouwe viervoeters. Onderzoekers van de Universiteit van Colorado beschrijven hun resultaten in het nieuwste nummer van het gratis toegankelijke tijdschrift eLIFE. Ze vergeleken monsters van bacteriën uit […]

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  • door dTHIP redactie

Cigarette Smoke Boosts Virulence in Staphylococcus Aureus

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ScienceDaily (Nov. 8, 2012) — Exposure to cigarette smoke has long been associated with increased frequency of respiratory infections — which are harder to treat in smoke-exposed people than in those who lack such exposures. Now Ritwij Kulkarni of Columbia University, New York, NY, and colleagues show that cigarette smoke actually boosts virulence of Staphylococcus aureus bacteria.

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  • op 29 november 2012
  • door dTHIP redactie

Reduced Costs for Staphylococcus aureus Carriers Treated Prophylactically with Mupirocin and Chlorhexidine in Cardiothoracic and Orthopaedic Surgery

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A multi centre double-blind randomised-controlled trial (M-RCT), carried out in the Netherlands in 2005–2007, showed that hospitalised patients with S. aureus nasal carriage who were treated prophylactically with mupirocin nasal ointment and chlorhexidine gluconate medicated soap (MUP-CHX), had a significantly lower risk of health-care associated S. aureus infections than patients receiving placebo (3.4% vs. 7.7%, […]

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  • op 28 oktober 2012
  • door dTHIP redactie