The Washing Machine as a Reservoir for Transmission of Extended-Spectrum-Beta-Lactamase (CTX-M-15)-Producing Klebsiella oxytoca ST201 to Newborns

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During the period from April 2012 to May 2013, 13 newborns (1 to 4 weeks of age) and 1 child in a pediatric hospital ward in Germany were colonized with Klebsiella oxytoca producing an extended-spectrum beta-lactamase (ESBL) (CTX-M-15). A microbiological source-tracking analysis with human and environmental samples was carried out to identify the source and transmission pathways of […]

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  • op 6 december 2019
  • door dTHIP redactie

Prevalence of faecal carriage of extended-spectrum β-lactamase (ESBL)- producing Escherichia coli in veterinary hospital staff and students

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Extended-spectrum β-lactamase (ESBL)-producing bacteria causing clinical infections are often also multidrug-resistant (MDR; resistance to ≥3 antimicrobial drug classes), therefore treatment options may be limited. High carriage rates of these potentially zoonotic bacteria have been found in livestock and companion animals. Therefore, people working in veterinary hospitals may be a high-risk population for carriage. This is the […]

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  • op 17 februari 2019
  • door dTHIP redactie

Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) isolated from bean sprouts in the Netherlands

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Community-acquired carriage and infections due to extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) are increasing worldwide, resulting in increased morbidity, mortality and healthcare costs. The origins of community-acquired ESBL-E car- riage and infections remain unclear. Bean sprouts are a potential source of Enterobacteria- ceae for the community, as illustrated by outbreaks of pathogenic Enterobacteriaceae in the past. The current study focuses on contamination […]

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  • op 9 september 2018
  • door dTHIP redactie

Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis

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Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient populations in hospitals around the world. Intensive care unit (ICU) patients are particularly susceptible to nosocomial infections due to indwelling devices such as intravascular catheters, drains, and intratracheal tubes for mechani- cal ventilation. The increased vulnerability of infected ICU patients demonstrates the importance of […]

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  • op 29 augustus 2018
  • door dTHIP redactie

Colonization sites in carriers of ESBL- producing Gram-negative bacteria

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Antimicrobial Resistance and Infection Control (2018) 7:52  – klik hier voor volledig artikel Auteurs: Joffrey van Prehn* , Anna M. Kaiser, Suzanne D. van der Werff, Rosa van Mansfeld and Christina M. J. E. Vandenbroucke-Grauls  Department of Medical Microbiology and Infection Control, VU university medical center, PK 1 X 124, P.O. Box 7057, 1007 MB Amsterdam, […]

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  • op 1 mei 2018
  • door dTHIP redactie

A Nosocomial Outbreak of Clinical Sepsis in a Neonatal Care Unit (NCU) in Port-Au-Prince Haiti, July 2014 – September 2015

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PLoS Curr. 2018 Mar 21;10. pii: ecurrents.outbreaks.58723332ec0de952adefd9a9b6905932. doi: 10.1371/currents.outbreaks.58723332ec0de952adefd9a9b6905932. Lenglet A1, Faniyan O2, Hopman J3. Abstract Introduction: Between July 2014 and September 2015, a neonatal care unit (NCU) in Port Au Prince, Haiti, experienced an outbreak of sepsis, most probably due to nosocomial transmission of Extended Beta Lactamase (ESBL) producing gram negative bacteria, included Klebsiella […]

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  • op 12 april 2018
  • door Corianne Meijer

High prevalence of MRSA and ESBL among asylum seekers in the Netherlands

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Migration is one of the risk factors for the spread of multidrug-resistant organisms (MDRO). The increasing influx of migrants challenges local health care systems. To provide evidence for both hospital hygiene measure and empirical antibiotic therapy, we analysed all cultures performed in asylum seekers between January 1st 2014 and December 31st 2015 for methicillin resistant Staphylococcus aureus (MRSA) and […]

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  • op 10 mei 2017
  • door dTHIP redactie

Trends in Extended Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae and ESBL Genes in a Dutch Teaching Hospital, Measured in 5 Yearly Point Prevalence Surveys (2010-2014)

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This paper describes the trends in prevalence of ESBL producing Enterobacteriaceae (ESBL-E) and ESBL genes, measured in five consecutive yearly Point Prevalence Surveys (PPS). All patients present in the hospital and in a day-care clinic (including patients on dialysis) on the day of the survey, were screened for perianal ESBL-E carriage. Perianal swabs were taken […]

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  • op 27 januari 2016
  • door dTHIP redactie

Measuring the quality of infection control in Dutch nursing homes using a standardized method; the Infection prevention RIsk Scan (IRIS)

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BACKGROUND: We developed a standardised method to assess the quality of infection control in Dutch Nursing Home (NH), based on a cross-sectional survey that visualises the results. The method was called the Infection control RIsk Infection Scan (IRIS). We tested the applicability of this new tool in a multicentre surveillance executed June and July 2012.

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  • op 21 april 2015
  • door dTHIP redactie

Extensive Dissemination of Extended Spectrum β-Lactamase– Producing Enterobacteriaceae in a Dutch Nursing Home

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Risk factors for rectal carriage of ESBL-E and transmission were investigated in an outbreak of extended-spectrum β-lactamase– producing Enterobacteriaceae (ESBL-E).   Rectal carriage of ESBL-E was determined in a cross-sectional survey by culture of perianal swabs or fecal samples. Both phenotypical and genotypical methods were used to detect the production of ESBL. Nosocomial transmission was […]

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  • door dTHIP redactie