Differences in risk-factor profiles between patients with ESBL-producing Escherichia coli and Klebsiella pneumoniae: a multicentre case-case comparison study

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Background: Generic epidemiological differences between extended-spectrum beta-lactamase (ESBL)-producingEscherichia coli (ESBL-EC) and Klebsiella pneumoniae (ESBL-KP), are poorly defined. Nonetheless, defining such differences and understanding their basis could have strategic implications for infection control policy and practice.

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  • op 19 november 2014
  • door J. Freeman

The sink as a correctable source of extended-spectrum β-lactamase contamination for patients in the intensive care unit.

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Het artikel waarvan hier eerder het opleidingsverslag was te lezen nu gepubliceerd in het Journal of Hospital Infection. Ilse Wolf Klik hier voor de link

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  • op 30 juli 2014
  • door Ada Gigengack

Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes

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Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic resistance among pathogens. This review aims to give an overview of the major horizontal transfer mechanisms and their evolution and then demonstrate the human lower gastro-intestinal tract as an environment in which horizontal gene transfer of resistance determinatns occurs. Finally, implications for antibiotic […]

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  • op 2 juli 2014
  • door dTHIP redactie

Dissecting the epidemiology of resistant Enterobacteriaceae and non-fermenters

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Blog by Jon Otter: It was a great privilege to speak at the HIS/IPS Spring Meeting. You can download my slides here. The meeting was entitled: “What’s that coming over the hill? Rising to the challenge of multi-resistant Gram-negative rods”. This, I think, is an (oblique) reference to the signature hit of a Welsh band ‘The […]

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  • op 30 juni 2014
  • door dTHIP redactie

Moeders als belangrijkste bron van ESBL bij neonaten: periodieke screening van moeders en neonaten ook zinvol in NL?

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OBJECTIVES: This study aimed to determine the prevalence of and risk factors for colonization with extended-spectrum β-lactamase-producingEnterobacteriaceae (ESBL-E) and methicillin-resistant Staphylococcus aureus (MRSA) in very low birth weight (VLBW; <1500 g) infants and their mothers. METHODS: This investigation was conducted in the perinatal centre at the Charité Berlin between May 2012 and June 2013. VLBW infants and their mothers were screened for colonization with ESBL-E and MRSA. Demographic and clinical data were obtained from the […]

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  • door dTHIP redactie

ICHE special edition on CRE and MDROs

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Infection Control and Hospital Epidemiology have once again excelled themselves in putting together a fine special edition on CRE and MDROs. Around this time last year I posted an article on the ICHE special edition on the role of the environment, and this special edition is equally important. I strongly recommend that you read the […]

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  • op 26 maart 2014
  • door dTHIP redactie

Landbouw-gerelateerde infectieziekten: Verkenning van risico’s in praktijk en lacunes in beleid

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Het Platform Landbouw, Innovatie & Samenleving heeft de missie maatschappelijke vraagstukken op het beleidsterrein van landbouw, visserij, natuur en voedselkwaliteit vroegtijdig te signaleren en hierover te adviseren aan de bewindslieden van EZ. De verschillende uitbraken van besmettelijke dierziekten in Nederland de afgelopen decennia vormden aanleiding voor het Platform om deze thematiek verder te verkennen. In een eerste gesprek over dit […]

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  • door dTHIP redactie

Duration of colonization with antimicrobial-resistant bacteria after ICU discharge

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PURPOSE: Readmission of patients colonized with antimicrobial-resistant bacteria (AMRB) is important in the nosocomial dynamics of AMRB. We assessed the duration of colonization after discharge from the intensive care unit (ICU) with highly resistant Enterobacteriaceae (HRE), methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant enterococci (VRE).

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  • op 18 maart 2014
  • door dTHIP redactie

Predictors of hospital surface contamination with Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: patient and organism factors

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The role of the hospital environment in transmission of ESBL-Klebsiella pneumoniae (ESBL-KP) and ESBL-Escherichia coli (ESBL-EC) is poorly defined. Recent data however suggest that in the hospital setting, ESBL-KP is more transmissible than ESBL-EC. We sought therefore to measure the difference in hospital contamination rates between the two species and to identify key risk factors for contamination of the […]

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  • door dTHIP redactie

Presentaties ECCMID online beschikbaar

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Afgelopen maand was in Berlijn het 23ste congres van de ECCMID (European Congress of Clinical Microbiology and Infectious Diseases). Voor iedereen die hier niet bij aanwezig was en voor degenen die nog iets terug willen kijken, worden alle presentaties beschikbaar gesteld via de website. Veel presentaties zijn via de webcast helemaal na te kijken.

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  • op 15 mei 2013
  • door dTHIP redactie