The clinical significance of carbapenem-resistant Klebsiella pneumoniae rectal colonization in critically ill patients: from colonization to bloodstream infection

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Purpose . To highlight the clinical significance of carbapenem-resistant Klebsiella pneumoniae (CRKP) rectal colonization by examining the risk factors for CRKP rectal colonization and subsequent bloodstream infection (BSI) in critically ill patients. Methodology . Prospective study of CRKP rectal colonization in an intensive care unit (ICU) during a 39-month period. CRKP strains isolated from both the blood cultures and corresponding rectal […]

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  • op 17 februari 2019
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Prevention of Colonization and Infection by Klebsiella pneumoniae Carbapenemase–Producing Enterobacteriaceae in Long-term Acute-Care Hospitals

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Background. Klebsiella pneumoniae carbapenemase–producing Enterobacteriaceae (hereafter “KPC”) are an increasing threat to healthcare institutions. Long-term acute-care hospitals (LTACHs) have especially high prevalence of KPC.

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A large, refractory nosocomial outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli demonstrates carbapenemase gene outbreaks involving sink sites require novel approaches to infection control

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Carbapenem-resistant Enterobacteriaceae (CRE) are a health threat, but effective control interventions remain unclear. Hospital wastewater sites are increasingly highlighted as important potential reservoirs. We investigated a large Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli (KPC-EC) outbreak and wider CRE incidence trends over eight years in the Central Manchester Foundation NHS Trust (CMFT), UK, to determine the impact of Infection Prevention and Control […]

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  • op 29 oktober 2018
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New Delhi Metallo-β-Lactamase–Producing Escherichia coli Associated with Endoscopic Retrograde Cholangiopancreatography — Illinois, 2013

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Infections with carbapenem-resistant Enterobacteriaceae (CRE)* are increasing among patients in medical facilities (1). CRE that produce Klebsiella pneumoniaecarbapenemase (KPC) have been responsible for much of the increase in the United States. However, New Delhi metallo-β-lactamase (NDM)–producing CRE have the potential to add to this burden. Since first reported in 2009, through 2012, 27 patients with […]

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  • op 9 januari 2014
  • door dTHIP redactie